Core Technology
■About artificial chromosome vector
The artificial chromosome is a vector having a minimal function and structure as a chromosome by removing the gene region from a natural human or mouse chromosome. It is possible to introduce Mb size giant genes and multiple genes. The artificial chromosome is maintained stably in the cell and is transmitted from the parent to children in mouse and rat.
■nA Versatile Platform for Advanced Genome Engineering
Artificial chromosome vectors exist independently without integrating into the host chromosomes. Because they can carry a wide variety of genes, they function as a highly versatile biological controller, directing cellular functions and reproducing natural or designed biological activities. Examples include animals producing fully human antibodies, rare disease model animals, and cells for functional evaluation.
